Table 2.
Top associated disease terms with non-synonymous SNVs in SNV-1 and SNV-35.
| Korean only SNVs | Order | Disease term | Gene count | %of all genes in the category | P value (raw) | P value (adjusted) |
|---|---|---|---|---|---|---|
| SNV-1/ns | 1 | Adhesion | 241 | 37.249 | 2.28E-62 | 3.44E-59 |
| 2 | Disease Susceptibility | 238 | 28.848 | 1.60E-39 | 1.21E-36 | |
| 3 | Genetic Predisposition to Disease | 231 | 28.589 | 1.04E-37 | 5.23E-35 | |
| 4 | Myocardial Infarction | 90 | 37.190 | 4.95E-24 | 1.87E-21 | |
| 5 | Urologic Diseases | 98 | 34.386 | 4.48E-23 | 1.13E-20 | |
| 6 | Subarachnoid Hemorrhage | 54 | 51.923 | 4.30E-23 | 1.13E-20 | |
| 7 | Metabolic Diseases | 162 | 26.471 | 6.55E-23 | 1.41E-20 | |
| 8 | Kidney Diseases | 95 | 34.672 | 1.04E-22 | 1.74E-20 | |
| 9 | Skin and Connective Tissue Diseases | 137 | 28.482 | 1.04E-22 | 1.74E-20 | |
| 10 | Nervous System Diseases | 176 | 25.360 | 1.48E-22 | 2.23E-20 | |
| SNV-35/ns | 1 | Nelson syndrome | 3 | 0.446 | 0.0102 | 0.0102 |