Table 3.
Top associated drug terms with non-synonymous SNVs in SNV-1 and SNV-35.
| Korean only SNVs | Order | Drug term | Gene count | %of all genes in the category | P value (raw) | P value (adjusted) |
|---|---|---|---|---|---|---|
| SNV-1/ns | 1 | adenosine | 133 | 27.883 | 3.47E-21 | 1.24E-18 |
| 2 | adenosine triphosphate | 87 | 29.097 | 1.46E-15 | 2.61E-13 | |
| 3 | immune globulin | 145 | 23.237 | 2.42E-15 | 2.88E-13 | |
| 4 | hydroxyurea | 30 | 46.154 | 9.01E-12 | 8.04E-10 | |
| 5 | glutathione | 84 | 24.633 | 7.75E-11 | 4.61E-09 | |
| 6 | phosphoric acid | 50 | 31.447 | 6.76E-11 | 4.61E-09 | |
| 7 | heparin | 55 | 29.255 | 1.72E-10 | 8.77E-09 | |
| 8 | bupropion | 38 | 35.185 | 3.41E-10 | 1.52E-08 | |
| 9 | rosuvastatin | 43 | 32.090 | 6.95E-10 | 2.76E-08 | |
| 10 | calcium chloride | 27 | 40.909 | 2.70E-09 | 9.64E-08 | |
| SNV-35/ns | 1 | mannitol | 2 | 10 | 8.23E-05 | 0.0001 |
| 2 | niflumic acid | 2 | 10 | 8.23E-05 | 0.0001 | |
| 3 | adenosine monophosphate | 2 | 1.961 | 0.0022 | 0.0022 | |