Table III.

H3K9-specific histone demethylase (HDM) activity in the JJ012 cell line and inhibition with different concentrations of proline-rich polypeptide-1 (PRP-1).

H3K9 HDM activity (RFU/h/μg)	H3K9 HDM activity (ng/h/μg)	PRP-1 (μg/ml)	Inhibition (%)
843	421	0.5	63
		1	74
		10	91

Total H3K9 HDM activity was estimated in JJ012 human chondrosarcoma cellS. H3K9 HDM activity was inhibited by PRP-1 in A dose-DEPENDENT manner, WITH 91% inhibition upon treatment with 10 μg/ml PRP-1. RFU, RELATIVE FLUORESCENCE UNITS.