Table I.
Factors | Patient no. (%)(n=25) | Median OS (months) | 5-year OS (%) | Log-rank P-value |
---|---|---|---|---|
Age (years) | ||||
<20 | 10 (40) | Unreached | 58 | 0.064 |
≥20 | 15 | (60) | 23.2 | 14 |
Gender | ||||
Male | 18 (72) | 25 | 21.6 | 0.35 |
Female | 7 (28) | 33.3 | 43 | |
Histological subtype | ||||
Chondroblastic | 8 (32) | 13.4 | 13 | 0.015 |
Other | 17 (68) | 33.3 | 37 | |
Tumor necrosis | ||||
<90% | 17 (68) | 23.2 | 8 | 0.011 |
≥90% | 6 (24) | Unreached | 69 | 69 |
ND | 2 (8) | |||
RFI (months) | ||||
<12 | 11 (44) | 24.6 | 30 | 0.74 |
≥12 | 14 (56) | 29 | 27 | |
Peri-PM chemotherapy | ||||
Yes | 20(80) | Unreached | 63 | 0.13 |
No | 5 (20) | 24.6 | 19 | |
Number of nodules | ||||
<3 | 12 (48) | 25 | 27 | 0.85 |
≥3 | 13 (52) | 24.8 | 29 | |
Laterality | ||||
Unilateral | 13 (52) | 25 | 33 | 0.58 |
Bilateral | 12 (48) | 29 | 26 | |
Size (cm) | ||||
<3 | 11 (44) | 32 | 36 | 0.91 |
≥3 | 11 (44) | 24 | 30 | |
ND | 3 (12) | |||
Metastasis during CTX | ||||
Yes | 3 (12) | 11.0 | 0 | <0.0001 |
No | 22 (88) | 29.0 | 33 | |
Detection of metastasis | ||||
At initial diagnosis | 5 (20) | 32.0 | 40 | 0.43 |
At recurrence | 20 (80) | 24.8 | 27 | |
Status of resection margins | ||||
R0 | 19 (76) | 25 | 38 | 0.36 |
R1 | 6 (24) | 29 | 0 | |
Visceral pleural involvement | ||||
Yes | 5 (20) | 13.1 | 0 | 0.007 |
No | 20 (80) | 32 | 39 |
OS, overall survival; ND, no data; RFI, relapse-free interval; PM, pulmonary metastasectomy; CTX, chemotherapy.