Table II.
Diagnostic performance of 18F-FLT PET and 18F-FDG PET for the evaluation of pulmonary lesions.
| Sensitivity | Specificity | PLR | NLR | DOR | Threshold effect | |
|---|---|---|---|---|---|---|
| 18F-FLT PET | ||||||
| Pooled estimates | 0.81 | 0.7 | 4.01 | 0.27 | 12.58 | P=0.383 |
| 95% CI | 0.74–0.87 | 0.61–0.77 | 1.62–9.88 | 0.20–0.37 | 6.81–23.24 | |
| Cochran-Q (P-value) | 3.85 (0.6973) | 40.61 (0.0000) | 32.15 (0.0000) | 3.74 (0.7114) | 8.95 (0.1766) | |
| I2 value, % | 0.00 | 85.20 | 81.30 | 0.00 | 32.90 | |
| 18F-FDG PET | ||||||
| Pooled estimates | 0.92 | 0.5 | 2.01 | 0.17 | 10.72 | P=0.645 |
| 95% CI | 0.86–0.95 | 0.41–0.58 | 1.38–2.93 | 0.10–0.29 | 5.51–20.87 | |
| Cochran-Q (P-value) | 2.51 (0.8670) | 15.56 (0.0163) | 18.92 (0.0043) | 4.30 (0.6360) | 6.46 (0.3734) | |
| I2 value, % | 0.00 | 67.50 | 68.30 | 0.00 | 7.20 |
PET, positron emission tomography; FLT, fluorothymidine; FDG, fluorodeoxyglucose; PLR, positive-likelihood ratio; NLR, negative-likelihood ratio; DOR, diagnostic odds ratio.