Figure 11.

A 64-year-old female with Anderson–Fabry disease. The septum thickness is increased, up to 17 mm (left ventricular mass index 95 g/m²). Myocardial T1 is uniformly low (in the range of 900 ms, as seen on five-chamber and short axis slices in A and B), which is consistent with sphingolipids deposition in this patient. A typical feature of patchy fibrotic involvement of the lateral basal wall is seen with focal T1 pseudo-normalization or even slight increase (approximately 1150 ms) and co-localized signal increase on LGE imaging (C).