Table 1.

Baseline maternal characteristics of 225 cohorts presenting in modified WHO I–IV

	All patients (n=225)	WHO I (n=73)	WHO II–IV (n=152)	p Value
Age at enrolment (years)	28.6±6.4	28.8±7.0	28.5±6.1	0.97
Ethnicity, n (%)
African or black	101 (45)	23 (32)	79 (52)	<0.0001
Mixed	72 (32)	15 (20)	56 (37)
White	34 (15)	19 (26)	15 (10)
Other (Arab, Indian, other)	18 (8)	16 (22)	2 (1)
General medical history, n (%)
Chronic hypertension	12 (5)	2 (3)	10 (7)	0.35
Hypercholesterolaemia	3 (1)	0 (0)	3 (2)	0.55
HIV	38 (12)	2 (3)	36 (24)	<0.0001
Syphilis	1 (0.4)	0 (0)	1 (1)	1.00
Tuberculosis	4 (2)	0 (0)	4 (3)	0.31
Clinical history and presentation, n (%)
Previously known CVD	93 (41)	40 (55)	53 (35)	0.006
Previously operated CVD	57 (25)	27 (37)	30 (20)	0.007
NYHA FC I-II	193 (86)	73 (100)	120 (79)	<0.0001
NYHA FC III-IV	32 (14)	0 (0)	32 (21)
SBP in mmHg	119±15	118±13	119±16	0.97
DBP in mm Hg	74±11	75±10	74±11	0.53
Heart rate in bpm	86±18	78±12	90±19	<0.0001
Weight in kg	72.1±16.8	72.5±12.5	72.1+18.6	0.30
Obstetric history, n (%)
Gestational age at presentation	n=188	n=66	n=122
<12 weeks	7 (4)	3 (5)	4 (3)
12–24 weeks	84 (45)	32 (48)	52 (43)	0.65
>24 weeks	97 (52)	31 (47)	66 (54)
Gravida (median, range)	2 (1–7)	2 (1–6)	2 (1–7)	0.0002
Para (median, range)	1 (0–5)	1 (0–4)	1 (0–5)	0.003
Nulliparous, n (%)	65 (29)	29 (40)	36 (24)	0.02
Twin pregnancies	3 (1)	0 (0)	3 (2)	0.30

A number of women were either not pregnant or presented postpartum. Gestational age at presentation percentages calculated towards 187, 66 and 121, respectively.

CVD, cardiovascular disease; DBP, diastolic blood pressure; NYHA FC, New York Heart Association Functional Class; SBP, systolic blood pressure.