Table IV.
Plasma concentrations of IFN-γ and IL-4 (pg/ml) and IFN-γ/IL-4 ratio.
| A, IFN-γ plasma concentration (pg/ml) | |||||||
|---|---|---|---|---|---|---|---|
| Groups | No. | T0 | T1 | T2 | T3 | T4 | P-value |
| I | 15 | 11.5±6.3 | 11.4±3.4 | 7.5±2.5 | 5.3±3.5 | 6.5±2.7 | <0.01 |
| II | 14 | 11.0±5.0 | 11.2±3.2 | 8.3±4.2 | 7.3±2.6 | 7.3±3.8 | 0.01 |
| III | 14 | 12.1±5.8 | 11.8±5.3 | 11.1±3.2 | 8.3±2.3 | 7.9±2.6 | 0.02 |
| IV | 14 | 12.0±4.3 | 11.3±3.6 | 11.2±5.6 | 8.9±4.5 | 8.6±3.1 | 0.14 |
| P-value | 0.95 | 0.98 | 0.03 | 0.03 | 0.31 | ||
| B, IL-4 plasma concentration (pg/ml) | |||||||
| Groups | No. | T0 | T1 | T2 | T3 | T4 | P-value |
| I | 15 | 5.2±1.2 | 5.3±2.0 | 7.0±2.0 | 6.9±2.0 | 7.7±2.3 | <0.01 |
| II | 14 | 5.2±2.0 | 5.7±3.0 | 7.0±3.0 | 6.5±2.3 | 6.5±2.1 | 0.34 |
| III | 14 | 5.4±1.7 | 5.4±2.2 | 5.5±2.7 | 6.3±1.9 | 6.0±2.5 | 0.76 |
| IV | 14 | 5.5±1.6 | 5.4±2.0 | 5.5±3.0 | 6.3±3.0 | 5.8±3.0 | 0.89 |
| P-value | 0.95 | 0.96 | 0.23 | 0.34 | 0.18 | ||
| C, IFN-γ/IL-4 ratio | |||||||
| Groups | No. | T0 | T1 | T2 | T3 | T4 | P-value |
| I | 15 | 2.6±1.8 | 2.5±1.0 | 1.5±0.5 | 1.0±0.8 | 1.0±0.6 | <0.01 |
| II | 14 | 2.9±2.0 | 2.7±1.0 | 1.6±0.3 | 1.4±0.7 | 1.2±0.8 | <0.01 |
| III | 14 | 2.7±2.0 | 2.6±0.8 | 2.1±0.2 | 1.2±0.8 | 1.2±0.6 | <0.01 |
| IV | 14 | 2.8±1.7 | 2.6±0.9 | 2.2±0.3 | 1.7±0.6 | 1.9±0.7 | 0.02 |
| P-value | 0.97 | 0.93 | <0.01 | 0.08 | 0.005 | ||
Differences IN IFN-γ between groups by time period: T0, no significance. T1, no significance. T2, I VS. III, P=0.02; I VS. IV, P=0.02. T3, I VS. III, P=0.02; AND I VS. IV, P<0.01. T4, no significance. Differences IN IFN-γ between time periods compared TO T0 for each group: I, T0 VS. T3, P<0.01; AND T0 VS. T4, P<0.01. II, T0 VS. T3, P=0.01; AND T0 VS. T4, P=0.01. III, T0 VS. T3, P=0.02; AND T0 VS. T4, P<0.01. IV, no significance. Differences IN IL-4 between groups by time period: T0, T1, T2, T3 and T4, no significance. Difference IN IL-4 between time periods compared TO T0 for each group: I, T0 VS. T2, P<0.01; T0 VS. T3, P=0.02; AND T0 VS. T4, P<0.01. II, III AND IV, no significance. Differences IN IFN-γ/IL-4 between groups by time period: T0, no significance. T1, no significance. T2, I VS. III, P<0.01; I VS. IV, P<0.01; II VS. III, P<0.01; AND II VS. IV, P<0.01. T3, I VS. IV, P=0.01. T4, I VS. IV, P<0.01; II VS. IV, P<0.01; AND III VS. IV, P<0.01. Difference S IN IFN-γ/IL-4 between time period S compared TO T0 for each group: I, T0 VS. T2, P<0.01; T0 VS. T3, P<0.01; AND T0 VS. T4, P<0.01. II, T0 VS. T2, P<0.01; T0 VS. T3, P<0.01; AND T0 VS. T4, P<0.01. III, T0 VS. T3, P<0.01; AND T0 VS. T4, P<0.01. IV, T0 VS. T3, P<0.01; AND T0 VS. T4, P=0.02.