Table 1.

Possible mediator of the CIH effects on CB chemosensory potentiation.

Mediator	References
Endothelin 1	Rey et al., 2006, 2007; Iturriaga, 2013
Endothelin-1 (dependent on ROS)	Pawar et al., 2009; Peng et al., 2013
Reduced NO production (reduced nNOS and eNOS-ir levels).	Marcus et al., 2010; Del Rio et al., 2011a; Moya et al., 2012
Angiotensin II (dependent on O2- production signaling through AT1 receptor)	Lam et al., 2008, 2012; Marcus et al., 2010; Peng et al., 2011; Fung, 2014
Pro-inflammatory cytokines	Iturriaga et al., 2009; Del Rio et al., 2011b, 2012; Lam et al., 2012