Table 2.
Average adjusted resting blood pressure change (mean ± SEM) after 6 mo of 80 mg atorvastatin or placebo among total sample and by drug and sex.
| Resting BP (mmHg) | Total sample | Atorvastatin | Placebo | |||
|---|---|---|---|---|---|---|
| Pre | Δ | Pre | Δ | Pre | Δ | |
| Total | n = 419 | n = 202 | n = 217 | |||
| SBP | 118.9 ± 0.6 | 0.5 ± 0.5 | 115.3 ± 0.9 | 0.8 ± 0.7 | 114.7 ± 0.8 | 0.3 ± 0.6 |
| DBP | 75.3 ± 0.5 | 0.3 ± 0.5 | 75.5 ± 0.6 | 0.4 ± 0.7 | 75.2 ± 0.6 | 0.5 ± 0.6 |
| MAP | 87.7 ± 0.7 | 0.2 ± 0.8 | 88.5 ± 0.8 | 0.0 ± 0.8 | 86.8 ± 1.1 | 0.5 ± 1.3 |
| Men | n = 203 | n = 99 | n = 104 | |||
| SBP | 117.2 ± 0.8 | 1.2 ± 0.7 | 117.7 ± 1.2 | 2.7 ± 1.0 | 116.6 ± 1.1 | −0.2 ± 1.0 |
| DBP | 76.5 ± 0.6 | 1.0 ± 0.7 | 75.0 ± 0.9 | 2.0 ± 1.0 | 77.0 ± 0.9 | 0.2 ± 0.9 |
| MAP | 89.3 ± 1.0 | 1.2 ± 1.0 | 90.1 ± 0.9 | 0.9 ± 1.2 | 87.7 ± 1.6 | 1.7 ± 1.8 |
| Women | n = 216 | n = 102 | n = 113 | |||
| SBP | 113.0 ± 0.8* | −0.1 ± 0.7 | 113.0 ± 1.2* | −1.0 ± 1.1* | 113.0 ± 1.2* | 0.8 ± 0.8 |
| DBP | 74.3 ± 0.6* | −0.4 ± 0.7 | 76.0 ± 0.9* | −1.2 ± 0.9* | 73.4 ± 0.9∗‡ | 0.8 ± 0.9 |
| MAP | 86.1 ± 0.9* | −0.7 ± 1.2 | 86.9 ± 0.9* | −0.8 ± 1.2 | 85.9 ± 1.5* | −0.7 ± 1.8 |
Adjusted for age, baseline BMI, baseline VO2peak, and sex.
Pre, baseline; Δ, after 6 months; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure.
* P < 0.05; men versus women.
‡ P < 0.05, atorvastatin versus placebo.