Table 2.
Blood and baseline parametersa
| Parameter | plt/plt/Ldlr−/− (n=9) ± SD | Control (n=9) ± SD | P-value |
|---|---|---|---|
| Leukocytes (/nL) | 2.50±0.91 | 4.18±2.33 | NS |
| Erythrocytes (/pL) | 4.23±2.02 | 5.23±2.69 | NS |
| Hemoglobin (g/dL) | 6.34±3.55 | 8.78±3.70 | NS |
| Thrombocytes (/nL) | 206.33±80.59 | 322.83±263.59 | NS |
| Triglycerides (mg/dL) | 473.3±78.82 | 768.6±142.50 | NS |
| Total cholesterol (mg/dL) | 660.0±216.8 | 780.88±109.62 | NS |
| LDL cholesterol (mg/dL) | 541.0±187.4 | 648.3±124.9 | NS |
| HDL cholesterol (mg/dL) | 22.29±6.89 | 26.0±7.48 | NS |
| Body weight (g) | 27.52±1.45 | 27.75±2.11 | NS |
| Length (cm) | 9.59±0.13 | 9.60±0.13 | NS |
Notes:
a
Body weight and length, lipid profile, and hematological parameters were measured on the day of tissue harvesting of plt/plt/Ldlr−/− mice and controls. All values are shown as means ± SD.
Abbreviations: SD, standard deviation; NS, not significant; LDL, low-density lipoprotein; HDL, high-density lipoprotein.