Table 4.
Multiplex ELISA results for different cytokines and chemokines in blood serum of mice
| Target protein | plt/plt/Ldlr−/− (n=9) pg/mL ± SD | Control (n=9) pg/mL ± SD | P-value |
|---|---|---|---|
| CCL2 (MCP-1) | 67.12±11.15 | 117.1±36.63 | 0.0111 |
| CCL3 | 124.2±115.1 | 46.61±22.74 | 0.0401 |
| CCL5 | 210.4±126.9 | 79.36±42.35 | 0.0055 |
| TNFα | 347.6±67.72 | 703.6±274.4 | 0.0115 |
| IFNγ | 292.7±37.32 | 613.7±298 | 0.0311 |
| IL-1α | 220±106 | 206.5±108.4 | NS |
| IL-1β | 95.85±26.75 | 183.2±75.59 | 0.0111 |
| IL-2 | 50.63±12.59 | 119.3±46.16 | 0.0115 |
| IL-3 | 37.19±83.90 | 83.90±38.55 | 0.0161 |
| IL-4 | 175.12±71.09 | 169.2±65.76 | NS |
| IL-5 | 42.84±25.62 | 39.80±19.33 | NS |
| IL-6 | 369.9±478.8 | 2539±2175 | 0.0025 |
| IL-10 | 85.27±34.63 | 83.85±45.67 | NS |
| IL-12 | 123.5±23.59 | 244.5±112.5 | 0.0311 |
| IL-17 | 41.90±5.52 | 93.71±36.33 | 0.0464 |
Note: All values are shown as means ± SD.
Abbreviations: ELISA, enzyme-linked immunosorbent assay; SD, standard deviation; NS, not significant.