Skip to main content
. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Rheum Dis Clin North Am. 2014 Sep 2;40(4):581–604. doi: 10.1016/j.rdc.2014.07.002

Figure 1. Visual representation of uric acid transport in the renal proximal tubule.

Figure 1

URAT1 (SLC22A12) and GLUT9 (SLC2A9) function to reabsorb uric acid while ABCG2 acts to secrete uric acid.

Adapted from Lipkowitz MS. Regulation of uric acid excretion by the kidney. Curr Rheumatol Rep 2012;14(2):179-88 and Reginato AM, Mount DB, Yang I, Choi HK. The genetics of hyperuricaemia and gout. Nat Rev Rheumatol 2012;8(10):610-21; with permission.