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. Author manuscript; available in PMC: 2014 Dec 2.
Published in final edited form as: J Trauma. 2009 Dec;67(6):1162–1168. doi: 10.1097/TA.0b013e3181ba3577

Figure 3.

Figure 3

Burn-induced phosphorylation of intestinal p38 MAPK is attenuated by PTX. p38 MAPK from intestinal extracts evaluated using Western blot (n ≥ 3 animals per group). (A) Burn injury results in an 8-fold increase in phosphorylated p38 MAPK at 2 hours after burn injury. Treatment with PTX after injury results in phosphorylated p38 MAPK levels similar to sham. (B) Phosphorylated p38 MAPK protein expression remains increased at 24 hours after burn. PTX continues to prevent the burn-induced phosphorylation of intestinal p38 MAPK. There is no difference in total p38 MAPK expression in either group. *p < 0.001 versus sham and †p < 0.001 versus burn at 2 hours. **p < 0.01 versus sham and ‡p < 0.01 versus burn at 24 hours.