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. Author manuscript; available in PMC: 2014 Dec 2.
Published in final edited form as: J Trauma. 2009 Dec;67(6):1162–1168. doi: 10.1097/TA.0b013e3181ba3577

Figure 4.

Figure 4

Activation of intestinal ERK ½ after severe burn is decreased by PTX. Phosphorylated ERK ½ measured from intestinal extracts using Western blot (n ≥ 3 animals per group). (A) PTX prevents the burn-induced phosphorylation of intestinal ERK ½ at 2 hours after 30% TBSA burn. (B) Phosphorylated ERK ½ decreases somewhat by 24 hours after injury but remains significantly higher than sham. Treated with PTX continues to limit intestinal inflammation, with phosphorylated ERK ½ expression similar to sham. There is no difference in total ERK ½ protein expression in either group. *p < 0.01 versus sham and †p < 0.01 versus burn at 2 hours. **p < 0.001 versus sham and ‡p < 0.01 versus burn at 24 hours.