TABLE III.

Correlations With HADS Depression and Anxiety Subscales and Variables of Interest, Controlling for Age and Gender

	Depression	Anxiety
Adherence
Mean adherence difficulty score (all items)	0.31***	0.21**
Had a problem remembering to take the chelator	0.21**	0.13
Questions only for patients taking oral chelators
Had a problem taking the chelator	0.16*	0.07
Questions only for patients taking deferoxamine
Had a problem preparing deferoxamine	0.24*	0.25*
Had a problem sticking yourself	0.33**	0.31**
Had a problem wearing the pump	0.39***	0.37***
Ferritin	0.06	−0.04
Quality of life (SF-36)
Physical component summary score	−0.42***	−0.34***
Mental component summary score	−0.59***	−0.64***
Disease severity
Number of secondary complications	0.10	0.02
Number of iron related complications	0.08	0.02
Number of transfusion related complications	0.02	−0.03

Note: HADS anxiety and depression: higher = more symptoms of anxiety and depression. Adherence: higher = more difficulty with adherence. SF-36: higher = better quality of life. Disease severity: higher = greater severity.

^***P < 0.001

^**P < 0.01

^*P < 0.05.