Table S1.
Quality scores of the studies included in this systematic review
| Year | Randomized | Blinded | Prospective study | Control group | Inclusion criteriadefined | Intervention defined | Outcome defined | Baseline characteristic similarity* | Intention-to-treat analysis | Details of drop out/deaths | Total score |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Studies using anakinra | |||||||||||
| 20081 | N | N | N | N | Y | Y | Y | Y | Y | Y | 6 |
| 20122 | Y | N | Y | Y | Y | Y | Y | Y | N | Y | 8 |
| 20133 | N | N | N | Y | Y | Y | Y | N | N | N | 4 |
| 20144 | N | N | Y | Y | Y | Y | Y | Y | Y | 7 | |
| 20135 | N | N | N | N | Y | Y | Y | Y | Y | Y | 6 |
| 20116 | N | N | N | N | Y | Y | Y | Y | Y | Y | 6 |
| 20137 | N | N | N | Y | Y | Y | Y | Y | Y | N | 6 |
| 20108 | N | N | N | N | Y | Y | Y | Y | N | Y | 5 |
| Mean score | 6 | ||||||||||
Note:
*
Baseline characteristic similarity included age, sex, and the progress of the disease.