Table 3.
Genotype distribution | Genotype | |||||
---|---|---|---|---|---|---|
Group | Genotype | Case | Control | OR (95%CI) p value | Model | OR (95%CI) p value |
PCV | CC | 117 | 106 | reference | Additive | 1.31(0.97-1.78) 0.0747 |
TC | 110 | 89 | 1.12(0.76-1.64) 0.5657 | Dominant | 1.24(0.86-1.79) 0.2560 | |
TT | 24 | 9 | 2.42(1.07-5.43) 0.0290 | Recessive | 2.29(1.04-5.05) 0.0351 | |
nAMD | CC | 92 | 106 | reference | Additive | 0.91(0.65-1.29) 0.5961 |
TC | 53 | 89 | 0.69(0.44-1.07) 0.0931 | Dominant | 0.76(0.50-1.16) 0.2088 | |
TT | 12 | 9 | 1.54(0.62-3.81) 0.3510 | Recessive | 1.79(0.74-4.37) 0.1936 | |
PCV + nAMD | CC | 209 | 106 | reference | Additive | 1.14(0.87-1.50)0.3390 |
TC | 163 | 89 | 0.93(0.66-1.32) 0.6801 | Dominant | 1.03(0.74-1.44) 0.8625 | |
TT | 36 | 9 | 2.03(0.94-4.37) 0.0660 | Recessive | 2.10(0.99-4.44) 0.0487 |
SNP: single nucleotide polymorphism.
PCV: polypoidal choroidal vasculopathy.
nAMD: neovascular age-related macular degeneration.
OR: odds ratio; 95% CI: 95% confidence interval.