Table 5.
Effect of SME on antioxidant profile
| Treatment | CAT (U/min ) | SOD (U/mg protein) | GSH-Px nM/min/mg protein | GSH (μM /min/mg protein) | GSR nM/min/mg protein) | TBARS(nM /min/mg protein) |
|---|---|---|---|---|---|---|
| Control | 6.0 ± 0.5++ | 18.7 ± 2.8++ | 64.7 ± 3.9++ | 2.12 ± 0. 2++ | 121.7 ± 6.4++ | 29.3 ± 1.2++ |
| 3 ml/kg CCl4 | 2.9 ± 0.6** | 9.9 ± 0.7** | 34.2 ± 6.3** | 1.03 ± 0.3** | 67.3 ± 3.5** | 53.17 ± 1.2** |
| 100 mg/kg SME + CCl4 | 5.0 ± 0.7++ | 16.5 ± 0.7++ | 52.4 ± 7.8++ | 1.90 ± 0.1++ | 111.2 ± 12.4++ | 38.7 ± 2.6++ |
| 200 mg/kg SME + CCl4 | 5.8 ± 0.9++ | 17.5 ± 0.8++ | 62.7 ± 5.6 | 2.03 ± .07 | 122.33 ± 5.28++ | 31.17 ± 1.4++ |
| 100 mg/kg sylimarin + CCl4 | 5.7 ± 0.5++ | 19.4 ± 0.3++ | 60.2 ± 5.3++ | 2.17 ± 0.04++ | 115.3 ± 9.14+ | 30.0 ± 2.7++ |
| 200 mg/kg SME alone | 5.9 ± 0.6++ | 20.9 ± 0.5++ | 66.8 ± 3.3++ | 2.09 ± 0.2++ | 120.2 ± 6.3++ | 31.2 ± 2.7++ |
Mean ± SE (n = 6 number).
**indicate significance from the control group at P < 0.01 probability level.
++indicate significance from the CCl4 group at P < 0.01 probability level.