Table 1.
Patient Characteristics
| Mutant BRAF | All (n=63) | V600 (n=36) | Non-V600 (n=27) | p-value |
|---|---|---|---|---|
| Median age, years Range | 65 (33-85) | 64 (48-79) | 66 (33-85) | 0.72 |
| Sex | 0.97 | |||
| Female | 34 (54%) | 19 (53%) | 15 (56%) | |
| Male | 29 (46%) | 17 (47%) | 12 (44%) | |
| Smoking history | 0.007 | |||
| Never smokers | 5 (8%) | 3 (8%) | 2 (7%) | |
| ≤15 pack year | 13 (21%) | 12 (33%) | 1 (4%) | |
| >15 pack year | 45 (71%) | 21 (58%) | 24 (89%) | |
| Histology Adenocarcinoma | 100% | 100% | 100% | |
| Stagea | 0.054 | |||
| I | 17 (27%) | 9 (25%) | 8 (30%) | |
| II | 4 (6%) | 2 (6%) | 2 (7%) | |
| IIIa | 11 (17%) | 3 (8%) | 8 (30%) | |
| IIIb | 4 (6%) | 2 (6%) | 2 (7%) | |
| IV | 27 (43%) | 20 (56%) | 7 (26%) | |
| Race | 0.48 | |||
| White, Non-Hispanic | 55 (87%) | 30 (83%) | 25 (93%) | |
| Asian | 3 (5%) | 2 (6%) | 1 (4%) | |
| Black | 3 (5%) | 2 (6%) | 1 (4%) | |
| White, Hispanic | 2 (3%) | 2 (6%) | 0 (0%) | |
a
Stage at initial NSCLC diagnosis, American Joint Committee on Cancer AJCC, staging system 7th edition