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. 2014 Nov 26;9:5461–5469. doi: 10.2147/IJN.S70777

Figure 1.

Figure 1

UV absorbance spectral profiles of incubation mixtures containing 35 mg/mL BSA and 20 mM D-ribose incubated with GNPs of different sizes (2 nm, 5 nm, and 20 nm) at 37°C for 21 days.

Notes: (A) All incubation mixtures had GNPs of varied total surface area. (B) All incubation mixtures had colloidal suspensions of the same total surface area. In both A and B, the control solutions included BSA (35 mg/mL) with D-ribose (20 mM) only. Spectral readings ranged from 250 nm to 400 nm and glycation products absorbed maximally at around 280 nm. Repeat experiments yielded similar UV absorption profiles for each of the incubation mixtures.

Abbreviations: UV, ultraviolet; BSA, bovine serum albumin; GNP, gold nanoparticles; TS, total surface area.