. Author manuscript; available in PMC: 2015 Nov 1.

Published in final edited form as: Clin Liver Dis. 2014 Aug 27;18(4):853–876. doi: 10.1016/j.cld.2014.07.006

Table 1.

TIPS versus Endoscopic Treatment in Secondary Prophylaxis for Vacriceal Bleeding: Results from Multiple Meta-Analysis.

Study Findings	References

	Luca et al., 1999³²	Papatheodoridis et. al, 1999³³	Burroughs and Vangeli, 2002³⁴	Zheng et al, 2008³⁵

No. of Pts	750	811	948	883
No. of Randomized Trials	11	11	13	12
No. of TIPS	372	403	472	440
No. Endoscopic Therapies	378	408	476	443
Recurrent Bleeding
TIPS, no. (%)	81 (21)	76 (18.9)	88 (18.6)	86 (19)
Endoscopic Therapy, no. (%)	196 (52)	190 (46.6)	210 (44.1)	194 (43.8)
NNT with TIPS	3.3	4	4	Not Reported
Post-Treatment Encephalopthy
TIPS, no. (%)	119 (35)	126 (34.0)	134 (28.4)	148 (33.6)
Endoscopic Therapy, no. (%)	65 (19)	70 (18.7)	83 (17.3)	86 (19.4)
Mortality
TIPS, no. (%)	109 (28)	110 (27.3)	130 (27.5)	111 (25.2)
Endoscopic Therapy, no. (%)	98 (26)	108 (26.5)	118 (24.8)	98 (22.1)

NNT – Number Needed to Treat

TIPS, transjugular intrahepatic portosystemic shunt