Table 2.
TIPS versus Large Volume Paracentesis in Treatment for Refractory Ascites
| Study Findings | References | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Lebrec et al57 | Rossle et al58 | Gines et al59 | Sanyal et al60 | Salnero et al61 | Narahara et al62 | |
| No. of pts | 25 | 66 | 70 | 109 | 66 | 60 |
| No. of TIPS pts | 13 | 29 | 35 | 52 | 33 | 30 |
| No. of LVP pts
|
12 | 31 | 35 | 57 | 33 | 30 |
| Improvement of ascites | ||||||
| TIPS no. (%) | 5 (38) | 16 (84) | 18 (51) | 30 (53) | 26 (79)** | 24 (80) |
| LVP no. (%)
|
0 (0) | 9 (43) | 6 (17) | 9 (16) | 14 (42)** | 8 (27) |
| Survival | ||||||
| TIPS % | 29* | 58* | 26* | 26 | 59* | 64* |
| LVP %
|
56* | 32* | 30* | 30 | 29* | 35* |
| Post-Treatment Encephalopathy | ||||||
| TIPS no. (%) | 3 (23) | 15 (51) | 27 (77) | 22 (39) | 20 (61) | 20 (66) |
| LVP % no. (%) | 0 (0) | 11 (35) | 23 (66) | 13 (23) | 13 (39) | 5 (17) |
*
Transplant-free survival after two years
**
Defined as treatment failure, which was defined as when a patient received at least 4 LVP within 1 month for episodes of recurrent tense ascites.
TIPS, tranjugular intrahepatic portosystemic shunt
LVP, large volume paracentesis