Figure 1.

Effects of GBT on oxaliplatin-induced cold and mechanical hypersensitivity. (a) The average tail withdrawal latency in response to cold stimuli prior to (left) and 3 days (middle) and 5 days (right) after an oxaliplatin (6 mg/kg, i.p.) injection. (b) The mechanical threshold in response to von Frey hair stimuli prior to (left) and 3 days (middle) and 5 days (right) after an oxaliplatin (6 mg/kg, i.p.) injection. Data are presented as mean ± S.E.M.^* P < 0.05, ^*** P < 0.001 versus NS/Vehicle; ^## P < 0.01, ^### P < 0.001 versus NS/Oxali by one-way ANOVA followed by Dunnett's post hoc test.