Table 1.
Retrospective series that evaluated patients with CNSm from EOC.
| Author, year (reference) | Regimen of chemotherapy* | Number of patients with CNSm | Median interval between diagnosis of EOC and CNSm in months (range) | Median survival after diagnosis of OC in months (range) | Median survival after diagnosis of CNS metastases in months (range) |
|---|---|---|---|---|---|
| Anupol et al., 2002 [6] | Cisplatin and paclitaxel | 15 | 22 (0–53) | 38 (9–82) | 6 (0–49) |
| Cohen et al., 2004 [7] | Cisplatin and paclitaxel | 72 | 22 (0–219) | 40.5 (21.5–60) | 6.3 (5–8) |
| Chen et al., 2011 [8] | Carboplatin and paclitaxel | 10 | 24.3 (7–55) | NA | 3 (0–16) |
| Kumar et al., 2003 [9] | Carboplatin and paclitaxel | 18 | 29 (0–101) | 30.5 (5–110) | 4 (1–74) |
| Tay and Ajesh, 2005 [10] | Carboplatin and paclitaxel | 4 | 16.5 (8–65) | NA | 19,5 |
| Kastritis et al., 2006 [11] | Carboplatin and paclitaxel | 8 | 17,2 | 67 (48–85) | 22 (12–34) |
*Adjuvant, palliative, or neoadjuvant chemotherapy received before diagnosis of CNSm.