Table 5.
Biological parameters evolution between day 0 and day 3
| AS + AQ | AL | |||||
|---|---|---|---|---|---|---|
| Parameters | D0 | D3 | P value | D0 | D3 | p value |
| Mean Hb level (g/dL) (±SD) | 10.53 (±1.98) | 9.39 (±2.74) | <10-4 | 10.57 (±1.84) | 8.72 (±2.88) | <10-4 |
| Anaemia (Hb level <11 g/dL) (%) | 58.6 | 70.9 | 0.014 | 57.4 | 79.5 | <10-4 |
| Patient with abnormal ALAT (<40UI/L) (%) | 79.79 | 90.40 | 0.012 | 75.90 | 81.89 | 0.20 |
| Patient with abnormal ASAT (<40UI/L) (%) | 55.32 | 84.07 | <10-4 | 51.79 | 79.47 | <10-4 |
| Mean bilirubin level (±SD) | 06.45 (±6.65) | 08.26 (±8.30) | 0.14 | 5.50 (±4.81) | 8.89 (±9.93) | 0.01 |
| Mean creatinine level (±SD) | 9.50 (±5.75) | 16.03 (±17.64) | <10-4 | 8.70 (±2.51) | 13.68 (±10.86) | <10-4 |
Abbreviations: AS-AQ, artesunate-amodiaquine; AL, artemether-lumefantrine; D, day; Hb, hemoglobin; ASAT, aspartate amino transferase; ALA, alanine amino transferase.