Table 1. Mortality rates, rate ratios, and rate differences in NLST participants by trial arm and by decile of PLCO_m2012 risk.

Category	Risk Percentile
	0–10	>10 to 20	>20 to 30	>30 to 40	>40 to 50	>50 to 60	>60 to 70	>70 to 80	>80 to 90	>90 to 100
CXR arm
Number of individuals in decile group	1	6	87	471	1,566	2,958	4,320	5,378	5,428	5,748
Number of deaths	0	0	0	1	7	19	35	81	135	254
Person-years of follow-up	6.67	38.21	555.29	3,062.57	10,274.54	19,309.86	28,065.96	34,721.42	34,543.86	35,454.52
Lung cancer mortality per 10,000 person-years	0	0	0	3.27	6.81	9.84	12.47	23.33	39.08	71.64
CT arm
Number of individuals in decile group	0	2	67	526	1,528	2,982	4,261	5,441	5,569	5,626
Number of deaths	0	0	0	2	5	12	35	61	106	230
Person-years of follow-up	0	13.71	427.03	3,484.44	10,005.65	19,479.05	27,763.18	35,323.81	35,690.19	35,004.87
Lung cancer mortality per 10,000 person-years	NA	0	0	5.74	5.00	6.16	12.61	17.27	29.70	65.71
Rate ratio (CT mortality/CXR mortality)	NA	NA	NA	1.76	0.73	0.62	1.01	0.74	0.76	0.92
Rate ratio 95% CI	NA	NA	NA	0.09 to 103.71	0.18 to 2.68	0.28 to 1.36	0.61 to 1.66	0.52 to 1.04	0.58 to 0.99	0.76 to 1.10
Rate difference per 10,000 person-years * (CT mortality − CXR mortality)	NA	0	0	2.48	−1.82	−3.68	0.14	−6.06	−9.38	−5.94
Rate difference 95% CI	NA	0–0	0–0	−7.74 to 12.68	−8.50 to 4.87	−9.31 to 1.95	−5.74 to 6.01	−12.74 to 0.62	−18.07 to −0.70	−18.17 to 6.30

PLCO_m2012 model risk decile boundaries were established in PLCO control smokers.

*Rate difference is incidence rate in CT arm per 10,000 minus incidence rate in CXR arm per 10,000. A negative absolute rate indicates a lower rate of lung cancer death in the CT arm compared to the CXR arm. PLCO_m2012 refers to the lung cancer risk prediction model described in [11].

NA, not applicable (because of zero occurring in denominator).