Figure 3. Knockdown of BMPRII attenuated BMP4 induced phosphorylation of P-Smad1/5/8, but not P-p38MAPK and P-ERK1/2 in PASMC.

(A), (B) and (C) show blots (left) and normalized bar graphs (right) of P-Smad1/5/8, P-p38MAPK, P-ERK1/2, t-Smad1/5/8, t- p38MAPK and t-ERK1/2, respectively. Bar values were means ± SEM (n  =  4 for each group). *P <0.01 vs. respective siNT control.