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. 2014 Dec 2;9(12):e112316. doi: 10.1371/journal.pone.0112316

Table 1. Patient data and characteristics before ECMO.

All No exchange System-exchange p-value
Patients (n) 265 182 83
Age (years) 50 (36–60) 50 (37–61) 50 (36–60) 0.844
Females (n; %) 90; 34 59; 32 31; 37 0.518
BMI (kg * m-2) 27.8 (24.7–33.1) 28.1 (24.8–32.9) 27.5 (23.9–34.2) 0.545
Ventilation (days) 1.0 (1.0–6.0) 1.0 (1.0–5.3) 2.0 (1.0–6.5) 0.431
SOFA score 11.0 (8.0–14.3) 12.0 (8.0–15.0) 11.0 (8.0–13.0) 0.067
LIS 3.33 (3.33–3.67) 3.33 (3.33–3.67) 3.33 (3.33–3.67) 0.660
ARF (n; %) 60; 22 55; 30 5; 6 ≤0.001
NE (µg/kg/min) 0.26 (0.10–0.51) 0.27 (0.10–0.51) 0.22 (0.08–0.53) 0.425
PaO2/FiO2 (mmHg) 65 (52–85) 65 (51–84) 69 (52–86) 0.554
PaCO2 (mmHg) 64 (51–80) 63 (50–79) 64 (54–88) 0.252
apH 7.24 (7.15–7.34) 7.23 (7.13–7.33) 7.24 (7.15–7.35) 0.453
TV (ml) 470 (396–562) 477 (399–565) 455 (358–560) 0.447
TV/kg pred. BW (ml/kg) 5.6 (4.2–6.7) 5.6 (4.4–6.7) 5.3 (3.8–6.7) 0.413
Minute ventilation (l/min) 10.6 (8.3–12.6) 11.0 (8.6–12.6) 10.5 (7.9–12.6) 0.517
PIP (cm H2O) 35 (30–39) 35 (30–39) 35 (30–40) 0.813
PEEP (cm H2O) 15 (13–18) 15 (13–18) 15 (13–18) 0.505
ECMO indication § 0.001
1 (n; %) 150; 57 92; 51 58; 70
2 (n; %) 53; 20 45; 25 8; 10
3 (n; %) 33; 12 28; 15 5; 6
4 (n; %) 29; 11 17; 9 12; 14

Data are presented as median (interquartile range) except for females and acute renal failure. SOFA, Sequential Organ Failure Assessment; LIS, Murray lung injury score; apH, arterial pH value; PaCO2, partial pressure of arterial carbon dioxide; PaO2/FiO2, ratio of partial pressure of arterial oxygen and fraction of inspired oxygen; PIP, peek inspiratory pressure; PEEP, positive end-expiratory pressure; TV, tidal volume; BMI, body mass index; ARF, acute renal failure; NE, Norepinephrine.

§

ECMO indications: 1, primary lung failure (bacterial, viral, fungal, aspiration pneumonia and H1N1 infection); 2, sepsis with secondary lung failure; 3, trauma with ARDS; 4, other pathologies (eg. pulmonary fibrosis, pulmonary hypertension, pulmonary emboli, extensive bronchiectasis, pulmonary bleeding, tracheal laceration).