Membrane remodeling behavior studied using the EM2 model with the N-BAR domain modelled as an isotropic homogeneous curvature field. (a) An initially vesicular membrane remains spherical when C0 = 0.0nm−1, and (b) the vesicular structure breaks up into a collection of smaller vesicles at higher values of C0; data has been shown for C0 = 0.14nm−1
(Reprinted from Biophys. J, 92
(10), G. Ayton, P. D. Blood, and G. A Voth, Membrane Remodeling from N-BAR Domain Interactions: Insights from Multi-Scale Simulation, 3595–3602, Copyright (2007), with permission from Elsevier).