Table 2.
Odds ratio estimates and 95% confidence intervals for the association of vitamin D status and atopic diseases diagnosed at the age of 10 years
| Outcome: at the age of 10 years | ||||||
|---|---|---|---|---|---|---|
| Outcome | OR (CI) | |||||
| 1. Quartile | 2. Quartile | 3. Quartile | 4. Quartile | Continuous [per 10 nmol/l] | ||
| Asthma male | Cases/Non-diseased (% Cases) | 21/271 (7%) | 16/309 (5%) | 14/282 (5%) | 15/312 (5%) | 66/1174 (5%) |
| Adjusted model1 | 1 | 0.59 (0.30;1.16) | 0.57 (0.28;1.17) | 0.58 (0.29;1.17) | 0.92 (0.82;1.03) | |
| Asthma female | Cases/Non-diseased (% Cases) | 4/301 (1%) | 8/290 (3%) | 8/285 (3%) | 9/280 (3%) | 29/1156 (2%) |
| Adjusted model1 | 1 | 2.20 (0.66;7.50) | 2.07 (0.61;7.05) | 2.58 (0.76;8.57) | 1.12 (0.97;1.30) | |
| Eczema | Cases/Non-diseased (% Cases) | 18/569 (3%) | 36/567 (6%) | 38/536 (7%) | 31/580 (5%) | 123/2252 (5%) |
| Adjusted model2 | 1 | 2.01* (1.12;3.60) | 2.27* (1.27;4.06) | 1.82 (1.00;3.31) | 1.09* (1.01;1.17) | |
| Hay fever or allergic rhinitis | Cases/Non-diseased (% Cases) | 57/536 (10%) | 77/539 (13%) | 66/513 (11%) | 67/548 (11%) | 267/2136 (11%) |
| Adjusted model2 | 1 | 1.28 (0.89;1.86) | 1.12 (0.76;1.64) | 1.07 (0.73;1.57) | 0.98 (0.93;1.04) | |
1Outcome = Vitamin D concentration + age + study + breastfeeding + BMI + highest parental education + family history.
2Outcome = Vitamin D concentration + age + sex + location of study + study + breastfeeding + BMI + highest parental education + single parent status + family history.
The OR estimates and 95% CI for the association of vitamin D status (serum 25(OH)D concentration in quartiles or as continuous variable [10 nmol/l]) and atopic diseases diagnosed at the age of 10 years are displayed. The asterisk indicate significant results at p < 0.05.