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. 2014 Nov 18;14:840. doi: 10.1186/1471-2407-14-840

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© Ackermann et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Hierarchical clustering of FOXP1 DNA methylation ratios. A total of 45 CpG units of FOXP1 were analyzed in 47 tumor samples and the neuroblastoma cell line IMR-32 (indicated in red). FOXP1 expression levels of the tumors (blue, low; green, high; as defined by the expression cutoff value for dichotomizing patient EFS) are indicated aside. DNA methylation values are indicated by colors ranging from dark red (non-methylated) to bright yellow (65% methylated). Poor quality data are indicated in grey. A histogram is given in the inset that indicates the frequency of each color in the hierarchical clustering.