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. 2014 Nov 18;14:840. doi: 10.1186/1471-2407-14-840

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© Ackermann et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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FOXP1 re-expression inhibits growth of neuroblastoma cells. FoxP1-induced changes in (a) cell viability (Trypan Blue dye exclusion analysis 6 days after induction of transgene expression), (b) cell proliferation (Alamar Blue assay 6 days after induction of transgene expression), (c) the proportion of cells showing apoptotic nuclei (72 h after induction of transgene expression), (d) the proportion of Annexin-V-positive cells (fluorescence-activated cell sorting (FACS)) and (e) cell cycle distribution (FACS). Each value represents the mean of triplicate experiments; error bars indicate S.D.