Table 2.

Multivariate Cox regression models based on EFS and OS, considering single prognostic markers and FOXP1 expression

Marker	Patients (N)	Available cases (N)	Hazard ratio	95% CI	P-value
Model considering single prognostic markers and FOXP1 expression based on EFS	476	471
Age (<18 months vs. >18 months)			1.43	0.96-2.13	0.077
Stage (stage 1-3, 4S vs. 4)			2.31	1.62-3.31	< 0.001
MYCN status (normal vs. amplified)			1.74	1.20-2.52	0.005
FOXP1 expression (cutoff EFS ≥27 840 vs. <27 840)			2.29	1.46-3.58	< 0.001
Model considering single prognostic markers and FOXP1 expression based on OS	476	471
Age (<18 months vs. >18 months)			2.95	1.60-5.42	< 0.001
Stage (stage 1-3, 4S vs. 4)			3.18	1.95-5.21	< 0.001
MYCN status (normal vs. amplified)			2.89	1.86-4.51	< 0.001
FOXP1 expression (cutoff OS ≥26 428 vs. <26 428)			1.79	0.98-3.26	< 0.001

Abbreviations: CI confidence interval, EFS event-free survival, OS overall surviaval, vs. versus.