Table 1.
Patient Demographic and Disease Characteristics (n = 337 analyzable participants)
| Characteristic | Tamoxifen Alone (n = 167) |
Tamoxifen + OFS (n = 170) |
||
|---|---|---|---|---|
| No. | % | No. | % | |
| Age, years | ||||
| Median | 46 | 44 | ||
| Range | 26-55 | 30-54 | ||
| 26-40 | 22 | 13.2 | 36 | 21.2 |
| 41-50 | 117 | 70.1 | 111 | 65.3 |
| 51-55 | 28 | 16.8 | 23 | 13.5 |
| Race/ethnicity | ||||
| White | 154 | 92.2 | 154 | 90.6 |
| Black | 7 | 4.2 | 9 | 5.3 |
| Other | 5 | 3.6 | 7 | 4.1 |
| Unknown | 1 | 0 | ||
| Hormone receptors | ||||
| ER positive, PgR positive | 147 | 88 | 149 | 87.7 |
| ER positive, PgR negative | 13 | 7.8 | 14 | 8.2 |
| ER positive, PgR unknown | 1 | 0.6 | 2 | 1.2 |
| ER negative, PgR positive | 4 | 2.4 | 4 | 2.4 |
| ER unknown, PgR positive | 2 | 1.2 | 1 | 0.6 |
| Tumor size, cm | ||||
| ≤ 1.0 | 22 | 13.2 | 15 | 8.8 |
| 1.1-2.0 | 117 | 70.1 | 126 | 74.1 |
| > 2.0 | 28 | 16.8 | 29 | 17.1 |
| Type of OFS | ||||
| LHRH | — | — | 61 | 36 |
| Oophorectomy | — | — | 72 | 42 |
| Radiation | — | — | 22 | 13 |
| Refused OFS | — | — | 15 | 9 |
| Surgical procedure | ||||
| Breast conservation | 97 | 58.1 | 112 | 65.9 |
| Mastectomy | 70 | 41.9 | 58 | 34.1 |
Abbreviations: ER, estrogen receptor; LHRH, luteinizing hormone-releasing hormone; OFS, ovarian function suppression; PgR, progesterone receptor.