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. Author manuscript; available in PMC: 2015 Aug 7.
Published in final edited form as: Nature. 2014 Jul 30;512(7512):44–48. doi: 10.1038/nature13613

Extended Data Figure 1. Primary enamel knot size predicts cusp number.

Extended Data Figure 1

Size of the primary enamel knot (day 2) and cusp number (day 7) for Eda null, Eda null + 10 ng ml−1 EDA, Eda null + 50 ng ml−1 EDA, and wild-type teeth. Reduced major axis regression for square root of μm2 are 0.0533 × −0.791, r2 = 0.613, P < 0.0001, n = 46. Enamel knot size does not increase substantially with higher EDA concentrations.