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. Author manuscript; available in PMC: 2014 Dec 2.
Published in final edited form as: Biol Chem. 2014 Sep;395(9):1003–1013. doi: 10.1515/hsz-2014-0122

Figure 2.

Figure 2

Phylogenetic tree of the Klk4, Klk5 and Klk7 genes (A) and the type-I functional branch lengths of these genes (B). (A) This tree was constructed by the ML method based on the JTT+G+I amino acid substitution model. The branches to Klk4 (Euarchontoglires and Laurasiatheria), Klk5 (Euarchontoglires, Laurasiatheria, Xenarthra/Afrotheria and Marsupialia) and Klk7 are supported by a bootstrap value of 99–100%. The scale is shown between Klk4 and Klk7. (B) The type-I branch lengths of each KLK gene cluster from their common ancestral gene, calculated using Diverge 2.0 (b4 = 0.641, b5 = 0.062, and b7 = 0.546), are illustrated. Note that b5 is much shorter than b4 (and b7), suggesting a functional divergence of Klk4 from Klk5.