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. Author manuscript; available in PMC: 2015 Nov 15.
Published in final edited form as: Biochem Pharmacol. 2014 Aug 30;92(2):389–402. doi: 10.1016/j.bcp.2014.08.025

Fig. 10. Binding mode of bendroflumethiazide and comparison of the binding modes of MET and thiazide diuretic hydrochlorothiazide to PXR’s LBD.

Fig. 10

(A) Docking mode three-dimensional (3D) interaction scheme of predicted binding orientation of bendroflumethiazide (shown in red) at the PXR LBD binding site. (B) Comparison of the binding mode of MET (red) and hydrochlorothiazide (grey) to PXR’s LBD.