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. Author manuscript; available in PMC: 2015 Nov 15.
Published in final edited form as: Biochem Pharmacol. 2014 Aug 30;92(2):389–402. doi: 10.1016/j.bcp.2014.08.025

Table 1.

Rifampicin and MET activities in CYP3A4 promoter luciferase reporter assays

Compounds HepG2 (EC50, μM) LS 180 (EC50, μM LS174T (EC50, μM)
Rifampicin 0.62 0.22 0.11
Metolazone 1.50 1.5 0.70