Fig. 6.

Effect of NC proteins on nucleic acid aggregation. ³³P-labeled DNA 128 was incubated with RNA 148 for 60 min at 37 °C in the absence or presence of increasing concentrations of NCp7, NCp9, and mutant 8A, under the conditions used for annealing in minus-stand transfer. The % aggregated nucleic acid present in the reaction mixture following incubation was plotted against protein concentration. The curves are highlighted in color as follows: NCp7, red; NCp9, green; mutant 8A, lavender.