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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: J Clin Neurosci. 2014 Jun 18;21(11):1881–1884. doi: 10.1016/j.jocn.2014.05.001

Table 3.

Patients from the current study with acute intracranial hemorrhage who received 4-factor prothrombin complex concentrate

Patient Diagnosis Initial INR Other relevant medication PCC dose Final INR Time from initial onsite INR to INR < 1.6 Time from administra tion of PCC to INR <1.6
1 Intraparenchymal supratentorial hemorrhage, intraventricular hemorrhage, hydrocephalus 2.5 (referring hospital), 1.9 (onsite) Vitamin K, FFP en route from referring hospital; FFP onsite 2500 U 1.1 110 minutes 30 minutes
2 Intraventricular hemorrhage 3.7 (referring hospital), 2.0 (onsite) Vitamin K, FFP prior to transfer 2000 U 1.1 241 minutes 113 minutes
3 Acute traumatic subdural hematoma (unilateral) 2.9 (onsite) Vitamin K 2500 U 1.2 9 hours 18 minutes 123 minutes
4 Acute traumatic subdural hematoma (bilateral) 4.0 (onsite) FFP 2500 U 1.1 157 minutes 28 minutes
5 Intraparenchymal cerebellar hemorrhage 2.6 (onsite) None 1500 U 1.1 160 minutes 35 minutes

FFP = fresh frozen plasma, INR = international normalized ratio, PCC = prothrombin complex concentrate.