Table 1.
Analysis | FA (Mean±SD) | MD (×10−3 mm2/s) (Mean±SD) | Da (×10−3 mm2/s) (Mean±SD) | Dr (×10−3 mm2/s) (Mean±SD) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neo-C | Neo-Hibo | p | Neo-C | Neo-Hibo | p | Neo-C | Neo-Hibo | p | Neo-C | Neo-Hibo | p | ||
TBSS | |||||||||||||
VM L | 0.25±0.03 | 0.20±0.02 | 0.013*, § | 0.72±0.04 | 0.76±0.07 | 0.25 | 0.90±0.05 | 0.92±0.11 | 0.74 | 0.61±0.03 | 0.67±0.05 | 0.024*, § | |
VM R | 0.28±0.02 | 0.22±0.01 | 0.003*, § | 0.77±0.06 | 0.77±0.06 | 0.88 | 1.00±0.09 | 0.95±0.06 | 0.36 | 0.65±0.05 | 0.69±0.06 | 0.36 | |
TS L | 0.31±0.04 | 0.23±0.05 | 0.037*, § | 0.76±0.03 | 0.85±0.10 | 0.049* | 1.00±0.07 | 1.05±0.11 | 0.38 | 0.64±0.02 | 0.75±0.11 | 0.03*, § | |
FX L | 0.37±0.02 | 0.27±0.01 | <0.001*, § | 0.94±0.06 | 1.10±0.09 | 0.004*, § | 1.32±0.08 | 1.41±0.11 | 0.16 | 0.75±0.05 | 0.95±0.09 | 0.001*, § | |
FX R | 0.34±0.02 | 0.24±0.04 | 0.001*, § | 1.08±0.07 | 1.26±0.13 | 0.011*, § | 1.49±0.07 | 1.57±0.12 | 0.18 | 0.88±0.08 | 1.11±0.13 | 0.004*, § | |
OR L | 0.55±0.02 | 0.48±0.03 | 0.003*, § | 0.67±0.02 | 0.70±0.06 | 0.44 | 1.14±0.02 | 1.11±0.12 | 0.63 | 0.42±0.02 | 0.49±0.03 | 0.042*, § | |
OR R | 0.41±0.02 | 0.34±0.04 | 0.002*, § | 0.69±0.08 | 0.69±0.03 | 0.88 | 1.02±0.11 | 0.97±0.07 | 0.39 | 0.50±0.03 | 0.56±0.01 | 0.03*, § | |
Volume-of-interest | |||||||||||||
VM L | 0.29±0.03 | 0.27±0.03 | 0.38 | 0.73±0.03 | 0.77±0.01 | 0.06 | 0.97±0.07 | 0.99±0.04 | 0.57 | 0.62±0.03 | 0.66±0.01 | 0.048* | |
VM R | 0.29±0.02 | 0.28±0.01 | 0.37 | 0.76±0.02 | 0.78±0.02 | 0.13 | 0.99±0.04 | 1.01±0.03 | 0.29 | 0.64±0.02 | 0.66±0.02 | 0.11 | |
TS L | 0.27±0.03 | 0.25±0.05 | 0.35 | 0.75±0.03 | 0.82±0.06 | 0.037* | 0.94±0.04 | 1.00±0.06 | 0.09 | 0.65±0.04 | 0.73±0.07 | 0.048* | |
TS R | 0.29±0.02 | 0.28±0.05 | 0.69 | 0.75±0.03 | 0.76±0.05 | 0.45 | 0.97±0.05 | 0.97±0.03 | 0.82 | 0.64±0.02 | 0.66±0.06 | 0.37 | |
FX L | 0.36±0.04 | 0.31±0.01 | 0.01* | 0.94±0.05 | 1.06±0.10 | 0.02* | 1.31±0.06 | 1.39±0.13 | 1.11 | 0.76±0.06 | 0.89±0.09 | 0.009* | |
FX R | 0.32±0.02 | 0.27±0.02 | 0.002*, § | 1.02±0.08 | 1.17±0.12 | 0.03* | 1.38±0.08 | 1.49±0.16 | 0.12 | 0.84±0.08 | 1.00±0.10 | 0.01* | |
OR L | 0.51±0.03 | 0.50±0.04 | 0.65 | 0.66±0.03 | 0.65±0.03 | 0.77 | 1.06±0.05 | 1.04±0.07 | 0.68 | 0.46±0.03 | 0.46±0.03 | 0.95 | |
OR R | 0.48±0.03 | 0.48±0.03 | 0.94 | 0.67±0.04 | 0.66±0.02 | 0.58 | 1.04±0.04 | 1.03±0.07 | 0.75 | 0.49±0.04 | 0.48±0.01 | 0.59 | |
CB L | 0.40±0.03 | 0.40±0.01 | 0.72 | 0.67±0.02 | 0.68±0.01 | 0.48 | 0.97±0.02 | 0.98±0.03 | 0.71 | 0.52±0.03 | 0.53±0.01 | 0.62 | |
CB R | 0.42±0.05 | 0.42±0.03 | 0.90 | 0.67±0.02 | 0.68±0.02 | 0.42 | 1.00±0.04 | 1.01±0.05 | 0.73 | 0.51±0.04 | 0.52±0.02 | 0.64 | |
CC | 0.62±0.03 | 0.63±0.03 | 0.80 | 0.78±0.02 | 0.79±0.03 | 0.49 | 1.41±0.05 | 1.44±0.04 | 0.47 | 0.46±0.03 | 0.47±0.04 | 0.76 | |
Tracts between hippocampus and VM | |||||||||||||
Tract1 L | 0.35±0.01 | 0.33±0.02 | 0.02* | 0.79±0.02 | 0.83±0.05 | 0.048* | 1.09±0.01 | 1.11±0.05 | 0.33 | 0.65±0.02 | 0.69±0.05 | 0.045* | |
Tract2 L | 0.30±0.02 | 0.29±0.03 | 0.21 | 0.78±0.02 | 0.80±0.02 | 0.21 | 1.03±0.02 | 1.04±0.06 | 0.83 | 0.65±0.02 | 0.68±0.01 | 0.035* | |
Tract1 R | 0.36±0.01 | 0.33±0.02 | 0.037* | 0.78±0.01 | 0.82±0.03 | 0.014* | 1.08±0.01 | 1.11±0.04 | 0.11 | 0.63±0.01 | 0.68±0.03 | 0.007*, § | |
Tract2 R | 0.33±0.01 | 0.32±0.03 | 0.37 | 0.76±0.01 | 0.77±0.01 | 0.40 | 1.04±0.02 | 1.04±0.04 | 0.98 | 0.62±0.01 | 0.64±0.01 | 0.24 |
The data were tested with independent t-test with significant level of p < 0.05 (* without multiple comparisons correction, § with FDR correction).
Abbreviation. VM: ventromedial prefrontal cortex; TS: temporal stem; FX: fornix; OR: optic radiations; CB: cingulate bundle; CC: corpus callosum; Tract1: tracts connecting hippocampus and VM through FX; Tract2: tracts connecting hippocampus and VM through TS; L: left; R: right; SD: standard derivation.