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. Author manuscript; available in PMC: 2015 Dec 17.
Published in final edited form as: Brain Res. 2014 Oct 12;0:40–54. doi: 10.1016/j.brainres.2014.09.057

Table 4. Testosterone Mediation Analyses.

Brain region Testosterone (ng/dl)
Indirect effect 95% CI
R rostral anterior cingulate cortex -0.003 [-.0211 - .0123]
R inferior frontal gyrus/anterior insula -0.001 [-.0201 - 0178]
 R inferior frontal gyrus 0.003 [-.0188 - .0251]
 R anterior insula -0.006 [-.0360 - .0250]
R middle temporal gyrus -0.007 [-.0617 - .0367]
L inferior frontal gyrus/anterior insula < .0001 [-.0295 - .0273]
 L inferior frontal gyrus -0.003 [-.0344 - .0262]
 L anterior insula 0.003 [-.0303 - .0358]
R precuneus 0.011 [-.0211 - .0466]
R middle frontal gyrus -0.004 [-.0318 - .0209]
L dorsolateral prefrontal cortex -0.001 [-.0543 - .0525]

A nonparametric bootstrap analysis of the indirect effects of testosterone was conducted for each significant cluster (and sub-cluster) identified in a sex-differences ANCOVA of spatial working memory. There were no significant indirect or mediation effects of testosterone. CI = Confidence Interval, R=right, L=left.