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. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: Acta Biomater. 2014 Aug 28;10(12):5021–5033. doi: 10.1016/j.actbio.2014.08.028

(a) Representative micro-computed tomography images of the bone defects implanted with CLF hydrogel containing different concentrations of BMP-2 (0, 0.5, 1, 2, or 5μg) at 4 weeks. (b) Quantification of regenerated bone volume within the bone defects. * denotes significant difference compared to the control CLF hydrogel groups with 0 μg BMP-2 (p<0.05).

(a) Representative micro-computed tomography images of the bone defects implanted with CLF hydrogel containing different concentrations of BMP-2 (0, 0.5, 1, 2, or 5μg) at 4 weeks. (b) Quantification of regenerated bone volume within the bone defects. * denotes significant difference compared to the control CLF hydrogel groups with 0 μg BMP-2 (p<0.05).