Table 1.
Mnx1WT | Mnx1null | |
---|---|---|
Fresh-fixed Diaphragm | 34+/−5 | 48+/−5 |
8 hr Diaphragm explant | 37+/−6 | 46+/−9 |
Stim 5.6 mHz | 31+/−9 | 18+/−11* |
Stim 1.7mHz | 39+/−11 | 25+/−10* |
Wnt3a | 40+/−10 | 38+/−9 |
Wnt3a +Nitrend. | 36+/−6 | 8+/−2* |
Wnt3a +RyR1null | 22+/−3* | 3+/−1* |
RyR1null | 43+/−7 | 48+/−8 |
Stim 5.6 mHz +RyR1null | 22+/−5* | 6+/−4* |
NRG1 | 42+/−10 | 25+/−6* |
NRG1 +RyR1null | 39+/−7 | 28+/−4* |
Agrin | 43+/−10 | 44+/−13 |
Agrin +RyR1null | 84+/−14* | 97+/−21* |
6-Benz cAMP | 41+/−11 | 44+/−14 |
6-Benz cAMP +RyR1null | 42+/−14 | 48+/−8 |
8-CPT-2′-O-Me cAMP | 35+/−14 | 44+/−13 |
8-CPT-2′-O-Me +RyR1null | 32+/−14 | 31+/−9 |
Roscovitine | 43+/−10 | 47+/−10 |
Roscovitine +RyR1null | 39+/−14 | 48+/−11 |
Average value from 5 diaphragm explants. Asterisks indicates p<0.005 (SEM)