Figure 5.
(A) Learning: Mean±SE swim distance (cm) across days on the Morris maze, collapsed across all trials. Young animals performed better than Aged Control and Aged Cognitive Training groups. (B) Overnight forgetting: Mean±SE difference in swim distance (cm) from trial 1 to trial 4 (trial 1 – trial 4), collapsed across days 2-5. Aged Cognitive Training females outperformed Aged Control females, an effect not found in males. (C) Probe trial: Mean±SE percent of total swim distance (cm) in the target NE vs. opposite SW quadrants during the probe trial. Young animals spent a greater percent of their total swim distance in the Target quadrant and less percent of total swim distance in the Opposite quadrant, than Aged Control animals, regardless of cognitive training or sex. Thus, all groups were able to equally localize the platform quadrant by the end of testing. * p < 0.05.