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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Clin Cancer Res. 2014 Oct 3;20(23):5986–5994. doi: 10.1158/1078-0432.CCR-14-0479

Table 4.

Probability of positive MRD post-induction based on five NK-related parameters.

Risk Category Group Blast PI-9 MFI NK FasL MFI NK Granzyme B MFI NK NKp46 % NK KIR2DL5A genotype Probability MRD positive (%)
Low 1 <=650 >415 > 4070 > 30 − 3.32 × 10−9
2 <=650 > 415 > 4070 > 30 + 1.34 × 10−8
3 <=650 <=415 > 4070 > 30 − 1.87 × 10−8
4 > 650 > 415 > 4070 > 30 − 2.36 × 10−8
5 <=650 > 415 > 4070 <=30 − 3.72 × 10−8
6 <=650 <=415 > 4070 > 30 + 7.57 × 10−8
7 > 650 > 415 > 4070 > 30 + 9.57 × 10−8
8 > 650 <=415 > 4070 > 30 − 1.33 × 10−7
9 <=650 > 415 > 4070 <=30 + 1.51 × 10−7
10 <=650 <=415 > 4070 <=30 − 2.09 × 10−7
11 > 650 > 415 > 4070 <=30 − 2.64 × 10−7
12 > 650 <=415 > 4070 > 30 + 5.38 × 10−7
13 <=650 <=415 > 4070 <=30 + 8.47 × 10−7
14 > 650 > 415 > 4070 <=30 + 1.07 × 10−6
15 > 650 <=415 > 4070 <=30 − 1.49 × 10−6
16 > 650 <=415 > 4070 <=30 + 6.03 × 10−6
Intermediate 17 <=650 > 415 <=4070 > 30 − 0.2
18 <=650 > 415 <=4070 > 30 + 1
19 <=650 <=415 <=4070 > 30 − 1.4
20 > 650 > 415 <=4070 > 30 − 1.7
21 <=650 > 415 <=4070 <=30 − 2.7
22 <=650 <=415 <=4070 > 30 + 5.3
23 > 650 > 415 <=4070 > 30 + 6.6
24 > 650 <=415 <=4070 > 30 − 8.9
25 <=650 > 415 <=4070 <=30 + 9.9
High 26 <=650 <=415 <=4070 <=30 − 13.3
27 > 650 > 415 <=4070 <=30 − 16.2
28 > 650 <=415 <=4070 > 30 + 28.3
29 <=650 <=415 <=4070 <=30 + 38.3
30 > 650 > 415 <=4070 <=30 + 44
31 > 650 <=415 <=4070 <=30 − 52.2
32 > 650 <=415 <=4070 <=30 + 81.6