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The BRPF1 bromodomain recognizes acetylated histones. (A) Schematic representation of domain modules within the human BRPF1 protein. (B) The MOZ/MORF HAT complex. (C) A ribbon diagram of the human BRPF1 bromodomain (yellow) in complex with the histone H2AK5ac peptide (blue sticks). (D) Top view of the H2AK5ac peptide in the binding pocket of the BRPF1 bromodomain. The structures were generated with Pymol [65].
