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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Gen Hosp Psychiatry. 2014 Jul 19;36(6):599–606. doi: 10.1016/j.genhosppsych.2014.07.004

Table 4.

Incremental Per Patient Costs and Effectiveness of Depression Care Interventions Compared to Usual Care

Study a Year Intervention Duration (mo.) Costs captured b Depression-Free Days Per Patient Incremental Outpatient Costs Per Patient (dollars) QALY Method d
Int Dir Ind In Trial Annualized Total Per DFD
Katon et al d [42,43] 1995
1998		 Psychiatrist collaborative care 6 ✓ ✓ 15.8 31.6 383 24.24 None
Katon et al d [43,44] 1996
1998		 Psychologist collaborative care 6 ✓ ✓ 13.4 26.8 471 35.15 None
Schulberg et al [13,45] 1996
1998		 Pharmacotherapy or Interpersonal psychotherapy 12 ✓ ✓ ✓ 49–58 49–58 - 13.14–17.56 DFD
$11,270–$19 510
Katzelnick et al [46,47] 2000
2001		 Depression care management 12 ✓ ✓ 47.4 47.4 675 14.24 None
Simon et al d [48] 2000 Telephone care management 6 ✓ ✓ 12.6 25.2 130 10.32 None
Simon et al [14] 2001 Stepped collaborative care 6 ✓ ✓ 16.7 33.4 242 14.49 None
Schoenbaum et al [15] 2001 Quality improvement 24 ✓ ✓ 36.5 36.5 - - DFD, SF-12
$9.478–$36,467
Katon et al [16] 2005 Collaborative care (late-life) 12 ✓ ✓ 52.6 52.6 - 2.76 DFD
$2,519–$5,037
Rost et al [49] 2005 Depression care management 24 ✓ ✓ ✓ 59.4 29.7 470–701 7.91–11.80 DFD
$9,592 to $14,306
Choi-Yoo et al 2014 Telecare management (cancer) 12 ✓ 60.3 60.3 1189 19.72 DFD, SF-12, EQ5D, Global QoL
$10,829–$73,287
a

All studies except that by Choi-Yoo were conducted in primary care populations. An additional primary care study by Pyne et al [33] showed no significant incremental effect of the intervention on depression-free days.

b

Int = intervention costs. Dir = other direct health care costs not related to intervention. Ind = indirect costs

c

If quality-adjusted life years (QALYs) calculated in article, the method (metric) used to calculate QALYs. DFD = depression-free days. SF-12 = Medical Outcome Study 12-item Short-Form. EQ5D = 5-item EuroQoL. Global QoL = single item overall quality of life.

d

Some of DFD data and/or cost per DFD not in original article(s) but in summary table in Simon et al 2001 article [14]