Table 2.

Combination Therapies for Murine GLD

Therapies	Lifespan			References
Therapies	Single	Combined	Response	References
L-cycloserine	56 days	112 days^*	Syngergistic	54
BMT	51 days	112 days^*	Syngergistic	54
VEGF	^**	50 days	Insignificant	55
BMT	41 days	50 days	Insignificant	55
Antioxidants	^**	48 days^*	N/A	56
Dietary Galactose Elimination	^**	48 days^*	N/A	56
N-acetyl cysteine (antioxidant)	37 days	38.5 days	Insignificant	57
BMT	^**	38.5 days	Insignificant	57
Single ICV ERT	51 days	59 days	Additive	32
BMT	^**	59 days	Additive	32
IV Lentivirus-GALC	50 days	75 days	Synergistic	58
HSC administration without preconditioning	60 days	75 days	Synergistic	58
IC AAV2/5-GALC	49 days	104 days^*	Synergistic	11
BMT	44 days	104 days^*	Synergistic	11
IC+IT AAV2/5-GALC	71 days	123 days	Synergistic	10
BMT	^**	123 days	Synergistic	10

Mean lifespans. All other life spans are represent ed by the median

^**

Lifespan for the indicated control single-therapy condition not reported in the paper cited, but may be available in other papers (See Table 1)